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ABBOTICIN Usage, Indication, Contraindication, Dosage, Precautions, and everything you should be familiar with

Want to know about Abboticin / Abboticine? If yes then you are at the right place. In this post we will tell you what is Abboticin or Abboticine (name differ from country to country), why it is used / indications, side effects of abboticin, dosage, composition, as well as other important information you should surely learn before taking this medicine.
Syrup Abboticin
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Indication of ABBOTICIN Drug

  • Abboticin is an antibiotic belonging to the macrolide class.
  • It is used in the treatment of various infectious diseases, including those of the lung, bronchus, skin, nose, throat, mouth and teeth, of the genital tract.

Presentation of Abboticin

  • Oral Suspension: 60 ml bottle.
  • Capsules
  • Tablets

ABBOTICIN Composition

  1. Erythromycin .......200 mg 
  2. Sucrose .................1.5 g.

Abbotocin Contraindication 

This drug should not be used in the following cases:
If you are allergic to macrolides, in association with medicinal products containing cisapride, pimozide, bepridil, mizolastine, ergotamine or dihydroergotamine.

Warnings About Abboticin

Precautions are necessary in case of liver failure.
This medicine contains sugar (sucrose) in significant amounts, diabetic patients should not use Abboticin .

ABBOTICIN Interaction with other medicines

Abboticin should not be using with medical products containing:
  1. Ergotamine or dihydroergotamine: danger of ergotism. 
  2. Cisapride, pimozide, bepridil or mizolastine: risk of torsades de pointes. 
  3. It can interact with drugs that contain one of the following substances: 
    • Bromocriptine, cabergoline, buspirone, carbamazepine, ciclosporin, ebastine, theophylline, aminophylline, tolterodine or triazolam.
  4. Inform your doctor if you have taken any lipid-lowering product from statin family, an anticoagulant or oral medication containing digoxin, lisuride or sildenafil.

Directions for use and dosage of ABBOTICIN

  • The oral suspension is reconstituted by adding water into the bottle equal the mark printed on bottle. Shake well before each time you use Abboticin.
  • This medicine is taken preferably just before meals 2 to 3 times a day.

General dose:

  • Infant and child up to 30 kg: 1 tea spoon per 5 kg per day.
  • For a 10 kg weighting child: 1 tea spoon, 2 times a day. 

Advice

The doctor sometimes prescribes Levy to identify the organism causing the infection and test its sensitivity to antibiotics. The result of this review may false if you take self-medication.
Do not take and do not give antibiotics without medical advice.

The possible impression of fatigue is not due to the antibiotic, but the infection itself.

The reconstituted oral suspension remains useful for one week in the refrigerator.

Possible side effects of the drug ABBOTICIN

  • Nausea, vomiting, diarrhea, stomach pain.
  • Allergic skin.
  • Increased transaminases, hepatitis (exceptional).

Pharmacokinetics of ABBOTICIN


The serum concentrations achieved varies depending on the dose and rate of administration. As a guideline may be stated that after administration of 500 mg for 30 minutes, a serum concentration of 10 micrograms / ml or greater are expected. Erythromycin is widely distributed to various tissues you. Variable data on the plasma protein binding is present, but usually referred it to 60-80%. Especially high concentrations are obtained, depending on the discharge conditions, the liver and bile. Erythromycin passes, however modestly through the blood brain barrier one. Place Tapas Agen can be estimated at about 10%. In normal hepatic function erythromycin is concentrated in the liver and excreted mainly via the bile and feces , which means that the anaerobic intestinal flora may be affected. Only a small portion, less than 5% is excreted through the urine and erythromycin can be given in an unchanged dose in patients with impaired renal function.

Preclinical data about ABBOTICIN

Oral long-term studies with erythromycin in rats, up to 400 mg / kg / day and in mice up to 500 mg / kg / day showed no evidence of tumorigenicity. Attempted mutagenicity studies revealed no genotoxic potential.
No evidence of teratogenicity or other adverse effects on reproduction were observed in female rats at oral gavage at 350 mg / kg / day (7 times the dose of one-to-human) of erythromycin before and during mating, during pregnancy and during the weaning of two successive litters.

We hope you are now familiar with Abboticin usage, side effects as well as other perspectives of the this medicine. Still if you are confused or you have other questions in your mind feel free to use the comment box below. Have a healthy and peaceful living.

Good luck.

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